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Man spends the greater portion of his life in sub-optimum states of consciousness. The paper reviews the experimental literature describing normal human performance at different levels of drowsiness and sleep, as these states are defined by electroencephalographic patterns. Among the types of behavioral responses to stimuli discussed are reflexes, simple movements, detection (i.e. arousal to external stimuli and awareness of internal states), discrimination, learning, and recall. Non-behavioral electroencephalographic responses are also described. Suggestions are made for future research.

Active shooter incidents represent an increasing threat to American society, especially in commercial and educational buildings. In recent years, a wide variety of security countermeasures have been recommended by public and governmental agencies. Many of these countermeasures are aimed to increase building security, yet their impact on human behavior when an active shooter incident occurs remains underexplored. To fill this research gap, we conducted virtual experiments to evaluate the impact of countermeasures on human behavior during active shooter incidents. A total of 162 office workers and middle/high school teachers were recruited to respond to an active shooter incident in virtual office and school buildings with or without the implementation of multiple countermeasures. The experiment results showed countermeasures significantly influenced participants' response time and decisions (e.g., run, hide, fight). Participants' responses and perceptions of the active shooter incident were also contingent on their daily roles, as well as building and social contexts. Teachers had more concerns for occupants' safety than office workers. Moreover, teachers had more positive perceptions of occupants in the school, whereas office workers had more positive perceptions of occupants in the office.

This paper identifies the mechanism by which patients with multiple sclerosis develop secondary autoimmunity after treatment with the lymphocyte-depleting humanized monoclonal antibody alemtuzumab (Campath-1H). In identifying this mechanism, it shows that T-cell homeostatic proliferation can lead to autoimmunity in humans. Alemtuzumab is one of the most effective treatments of multiple sclerosis tested to date; it is currently licensed in the European Union and under consideration by the Food and Drug Administration. Understanding what drives its most significant side effect is of clear clinical importance.

Economic globalization has caused an increase in inequality between developed and developing countries. This essay will interpret the impact economic globalization has on inequality, the cause of this phenomenon, and give out suggestions for developed countries to decrease inequality by studying the case of French and Niger cooperating in Uranium mining. France, with advanced technology and massive demand for Uranium, cooperates with Niger which is a poor biased country but preserves massive amounts of Uranium. Uranium mining in Niger has caused income inequality, environmental inequality, and inequality of work conditions. Because Uranium mining created radiation and pollution which is harmful to both workers and the environment, and Niger gets profits that are lower than the average price while France gains the massive electricity produced by Uranium at a low price. The essay will explain the increase of inequality through the theory of inequality exchange, a central concept in the investigation of world system theory, and it is also a classic problem in foreign Marxist development economics research.

AbstractA previous study on key farm performance indicators for animal welfare incidents in Ireland provided anecdotal evidence to suggest that farm animal welfare standards are often underpinned by social and human health‐related factors among farmers. The present study took an exploratory approach to identify these factors and how they influence farm animal neglect. Semi‐structured interviews were conducted with farmers. Identified factors included farming difficulties associated with age and help on the farm (n = 5), mental health‐related problems (n = 4), and differing perceptions of animal welfare (n = 4). Stress was a prevalent theme. Evidence suggests that these negative human factors impact on farmers' ability to carry out farm management activities. Poor uptake of support services was noted and barriers included resistance, self‐reliance and an inability to talk openly about mental health problems. Initiatives such as the early warning system, aimed at reducing the incidence of farm animal neglect in Ireland, should be understood as often involving a human element. In particular, further research is required into how mental health problems may lead to altered or reduced regard for animal welfare.