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The paper presents the results of qualitative field research about the phenomenon of NEETs - Not (engaged) in Education, Employment or Training - investigated with the constructivist Grounded Theory methodology. The research, which involved 82 young people aged between 18 and 24 years, began in November 2015 and ended with the analysis of data collected in December 2018. In line with the methodological indications of the constructivist Grounded Theory (GT) (Charmaz, 2000, 2006, 2014), field research was immediately accompanied by open coding, using all that was useful for saturation of the categories.The constant critical reflection, conducted throughout the process of my research, has led to detect and define 3 core categories that are fundamental to the definition of a substantive theory. The permanent orientation emerges as a social need because it promotes and increases the psychological well-being of NEETs. The comparison between the "initial" questions of research and the 3 core categories, conceptually valid, allowed me to start the process of focusing and analyzing the possible correlations. Correlations capable of supporting a scientifically strong definition, for the proposal of a substantive theory, emerging from the three initial questions of the research.1. How do you "selfassess" NEETs with respect to the world of work? Psychological area: to understand the characteristics of the NEET individual. How to contribute to its identity awareness about operating (occupying and acting) a role. To train him/her to reflect on his/her own interests, in accordance with his/her own authentic purposeful Self (Di Fabio, 2014). The question aims to understand how:a) to increase the capacity to make choices (Self confidence in decision making);b) to make them feel/perceive that they are ready (Self efficacy and Self capability);c) to raise the skills to manage problems (Self-empowerment and problem solving).2. How do NEETs live their "condition"? Psychosociological area: to investigate the context and environment of NEETs' life. The answers to this question must allow them to understand what they are, first and foremost:a) the causes to which they attribute their current NEET situation (external/internal);b) the roads they would like to take to move towards work (Self orientation);c) their thoughts and attitudes towards current social policies (active/passive).3. How do you represent the labour market? Sociopsychological area: relationship aspect; ability to stay in relationships. In the answers you want to understand:a) what they thought when they were at school in the world of work (imagination about their own future);b) how their thoughts on the world of work are today compared to those years (alignment to their own reality).c) what knowledge, what information they possess of the working possibilities of their territory (awareness of employment opportunities). Keywords: NEETs, Self-empowerment, purposeful Self, Self orientation, resiliency, decision making. Abstract in italiano Il documento presenta i risultati della ricerca sul campo qualitativa sul fenomeno dei NEET - Non (impegnati) nell'istruzione, nell'occupazione o nella formazione - indagati con la metodologia costruttivista della Grounded Theory. La ricerca, che ha coinvolto 82 giovani di età compresa tra 18 e 24 anni, è iniziata a novembre 2015 e si è conclusa con l'analisi dei dati raccolti a dicembre 2018. In linea con le indicazioni metodologiche della Grounded Theory (Charmaz, 2000, 2006, 2014), la ricerca sul campo è stata immediatamente accompagnata da una codifica aperta, utilizzando tutto ciò che è stato utile per la saturazione delle categorie.La costante riflessione critica, condotta durante tutto il processo della mia ricerca, ha portato a rilevare e definire 3 categorie fondamentali che sono fondamentali per la definizione di una teoria sostanziale. L'orientamento permanente emerge come un'esigenza sociale perché promuove e aumenta il benessere psicologico dei NEET. Il confronto tra le domande "iniziali" della ricerca e le 3 categorie fondamentali, concettualmente valide, mi ha permesso di iniziare il processo di focalizzazione e analisi delle possibili correlazioni. Correlazioni in grado di supportare una definizione scientificamente forte, per la proposta di una teoria sostanziale, che emerge dalle tre domande iniziali della ricerca.1. In che modo NEET "selfassess" rispetto al mondo del lavoro? Area psicologica: comprendere le caratteristiche dell'individuo NEET. Come contribuire alla consapevolezza dell'identità sull'operare (occupare e recitare) un ruolo. Formarlo per riflettere sui propri interessi, in accordo con il proprio Sé autentico e propositivo (Di Fabio, 2014). La domanda mira a capire come:a) aumentare la capacità di fare delle scelte (fiducia in se stessi nel processo decisionale);b) farli sentire / percepire di essere pronti (autoefficacia e capacità di auto);c) aumentare le competenze per gestire i problemi (auto-responsabilizzazione e risoluzione dei problemi).2. In che modo i NEET vivono la loro "condizione"? Area psicosociologica: indagare il contesto e l'ambiente della vita dei NEET. Le risposte a questa domanda devono consentire loro di capire cosa sono, innanzitutto:a) le cause alle quali attribuiscono la loro attuale situazione NEET (esterna / interna);b) le strade che vorrebbero percorrere per spostarsi verso il lavoro (orientamento personale);c) i loro pensieri e atteggiamenti nei confronti delle attuali politiche sociali (attivo / passivo).3. Come rappresenti il mercato del lavoro? Area socio-psicologica: aspetto relazionale; capacità di rimanere in relazione. Nelle risposte che vuoi capire:a) cosa hanno pensato quando erano a scuola nel mondo del lavoro (immaginazione per il proprio futuro);b) come sono oggi i loro pensieri sul mondo del lavoro rispetto a quegli anni (allineamento alla propria realtà).c) quali conoscenze, quali informazioni possiedono delle possibilità di lavoro del loro territorio (consapevolezza delle opportunità di lavoro). Parole chiave:NEETs, orientamento, resilienza, Self efficacy, decision making, Self empowerment, Self orientation. ; The paper presents the results of qualitative field research about the phenomenon of NEETs - Not (engaged) in Education, Employment or Training - investigated with the constructivist Grounded Theory methodology. The research, which involved 82 young people aged between 18 and 24 years, began in November 2015 and ended with the analysis of data collected in December 2018. In line with the methodological indications of the constructivist Grounded Theory (GT) (Charmaz, 2000, 2006, 2014), field research was immediately accompanied by open coding, using all that was useful for saturation of the categories.The constant critical reflection, conducted throughout the process of my research, has led to detect and define 3 core categories that are fundamental to the definition of a substantive theory. The permanent orientation emerges as a social need because it promotes and increases the psychological well-being of NEETs. The comparison between the "initial" questions of research and the 3 core categories, conceptually valid, allowed me to start the process of focusing and analyzing the possible correlations. Correlations capable of supporting a scientifically strong definition, for the proposal of a substantive theory, emerging from the three initial questions of the research.1. How do you "selfassess" NEETs with respect to the world of work? Psychological area: to understand the characteristics of the NEET individual. How to contribute to its identity awareness about operating (occupying and acting) a role. To train him/her to reflect on his/her own interests, in accordance with his/her own authentic purposeful Self (Di Fabio, 2014). The question aims to understand how:a) to increase the capacity to make choices (Self confidence in decision making);b) to make them feel/perceive that they are ready (Self efficacy and Self capability);c) to raise the skills to manage problems (Self-empowerment and problem solving).2. How do NEETs live their "condition"? Psychosociological area: to investigate the context and environment of NEETs' life. The answers to this question must allow them to understand what they are, first and foremost:a) the causes to which they attribute their current NEET situation (external/internal);b) the roads they would like to take to move towards work (Self orientation);c) their thoughts and attitudes towards current social policies (active/passive).3. How do you represent the labour market? Sociopsychological area: relationship aspect; ability to stay in relationships. In the answers you want to understand:a) what they thought when they were at school in the world of work (imagination about their own future);b) how their thoughts on the world of work are today compared to those years (alignment to their own reality).c) what knowledge, what information they possess of the working possibilities of their territory (awareness of employment opportunities). Keywords: NEETs, Self-empowerment, purposeful Self, Self orientation, resiliency, decision making.

Occurrence of ethical problem is forced them in research of total institutions by character. It belongs to biggest ethical problems in case of total institution in the course of research: - protection privacy respondent and at publication of result in accordance with staff; - behavior neutrality equal as well as subordinates; - disclosure secret environmental. Concentration on variable, which limit subjectivism of collected data has in research of total institutions in forceful winning objective data about functioning in accordance with society of reality ethical dilemmas meaning this exclusive not increasing simultaneously.

Candida auris is a pathogenic fungus that causes infections in people with weakened immune
systems. It is resistant to antimicrobial drugs, which complicates treatment. C. auris poses a
serious threat to public health, as it has a high resistance and contagiousness. The ribosome plays
an important role in the survival and development of this infection, and the search for inhibitors of the C. auris ribosome is of great importance. We used cryoelectron microscopy and single
particle analysis to obtain the three-dimensional structure of the C. auris ribosome. We describe
the architecture of the ribosome subunits and their interactions, providing valuable information
for the development of novel anti-fungals against C. auris.

The paper reviews Barbara Kaszkowska-Wandor's book Res publica (post) literaria. Od poetyki wspólnoty do postliteratury. The study into the etymology of the metaphor of the "literary republic" leads the author to consider fundamental questions concerning the role of literature in shaping communities and the ways in which literature impacts political reality. The author's erudition and bold methodological solutions allow her to answer those questions – often old and considered to be unanswerable – in an original, unobvious way. ; Tekst jest recenzją książki Barbary Kaszowskiej-Wandor Res publica (post) litteraria. Od poetyki wspólnoty do postliteratury. Badanie etymologii metafory "republiki literackiej" prowadzi autorkę do rozważania fundamentalnych pytań dotyczących roli literatury w kształtowaniu wspólnot społecznych i pytań o sposoby wywierania przez literaturę wpływu na rzeczywistość polityczną. Rozległa erudycja badaczki i stosowane przez nią odważne rozwiązania metodologiczne pozwalają jej udzielić na te pytania – bardzo stare i często uważane za nierozstrzygalne – oryginalnych, nieoczywistych odpowiedzi.

At the present stage of the development of linguistic science within the framework of the anthropocentric paradigm, many scientists most often consider language units in the linguocognitive and linguocultural aspects, which form the two dominant approaches in the research devoted to the problems of cognitive linguistics. Cognitive linguistics is currently one of the fastest developing and most promising areas of modern Russian linguistics. The article considers in detail the linguocognitive approach to the study of the concept. The author presents the most common definitions of the key term of cognitive linguistics within the framework of the linguocognitive approach — the concept. The paper presents and defines the key terms of linguocognitive science, namely, "concept", "conceptosphere", "cognitive base", "conceptual differential feature", "conceptual classification feature". The article also displays several typologies of concepts within the framework of the considered approach (representation, scheme, frame, concept, script, gestalt). The article presents a brief overview of modern methods of concept research: the procedure of semantic-cognitive research, the method of frame analysis, conceptual mapping, content analysis. The author of the article suggests two approaches to the analysis of the structure and functioning of the concept within the framework of the linguocognitive approach: static (non-discursive) and dynamic (discursive). In the first case, idiographic sources and the separate usages of concepts in various discourses are studied, and in the second, the concept is studied in line with the dynamic approach, when concepts are considered as phenomena of the dynamic level of interaction of language, consciousness, discourse, characterized by the potentiality of meanings and receiving certainty only at the discursive level, in the conditions of interaction of all these components.