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In Latin America, the immense existing biodiversity is associated with the abundance of enormous practically unknown regions and the presence of indigenous peoples, in some cases uncontacted. Along with the profusion of life forms that have been preserved over the years, the danger of genetic erosion caused by indiscriminate exploitation stands out on the one hand, and on the other the attempts at appropriation by institutions and natural persons, at the expense of the prejudice of the communities that inhabit those areas, of their habits of life and of their cultural practices. The purpose of this article is to reflect on these issues, based on the documentary information published by various authors. The examples presented also demonstrate that the region can take advantage of biodiversity for its own development, under a bioeconomy model, in which the efforts of science, education and production institutions coexist, supported by government policies of respect for the environment, indigenous populations and the legal protection of heritage.