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Given the multiple ways of regulations and market situations for new psychoactive substances (NPS), it is of interest how NPS users procure their drugs in different countries as well as in different user groups. Data comes from a face-to-face and online survey conducted in six EU countries, covering three groups of current (12-month) adult NPS users: (1) socially marginalized, (2) users in night life, and (3) users in online communities. While the supply situation differed considerably between countries, friends were the most prevalent source for buying, followed by online shops and private dealers. Marginalized users were more likely to buy from dealers, while online respondents showed the highest rates for buying online. While buying NPS from online or offline shops was relatively prevalent, we also found high rates for social supply and buying from dealers. A considerable part of this market may be classified as "social online supply," with private suppliers procuring their drugs online. The market features among marginalized users resemble more those of illicit drug markets than those for other NPS users. ; The NPS Transnational project received funding from the European Commission under NPS-HOME/2014/JDRU/AG/DRUG/7077. The project was co-financed by the Ministry of Science and Higher Education in Poland from financial resources for science in 2016–2017 granted for the implementation of an international co-financed project. The German partners received co-financing from the German Ministry of Health. ; info:eu-repo/semantics/publishedVersion