Sex and gender factors affecting metabolic homeostasis, diabetes and obesity
In: Advances in Experimental Medicine and Biology Volume 1043
In: Advances in Experimental Medicine and Biology Ser. v.1043
Intro -- Foreword -- Preface -- Introduction -- Contents -- Contributors -- Part I: Sex Differences in Diabetes and Obesity -- Epidemiology of Gender Differences in Diabetes and Obesity -- Introduction -- Gender Differences in Glucose Homeostasis -- Gender Differences in Type 2 Diabetes -- Gender Differences in Type 1 Diabetes -- Gender Differences in Metabolic Syndrome and Obesity -- Conclusions -- References -- Sex Differences in Body Composition -- Introduction -- Abdominal Adipose Tissue -- Muscle Mass -- Intramyocellular Lipids -- Intrahepatic Lipids -- Pericardial Adipose Tissue -- Neck Adipose Tissue -- Brown Adipose Tissue -- Tongue Adipose Tissue -- Summary -- References -- Cellular Mechanisms Driving Sex Differences in Adipose Tissue Biology and Body Shape in Humans and Mouse Models -- Introduction -- Sex Differences in Fat Distribution Are Genetically Regulated -- Few Studies Directly Compare Sex Differences in the Adipose Tissue Transcriptome -- Recent Advances in Understanding Sex Differences in Fat Accumulation -- Sex Differences in Regional Adipocyte Metabolism -- Recent Advances in Understanding Adipose Tissue Cellularity, Growth, and Remodeling -- Adipose Tissue Expansion via Hyperplasia Depends on the Recruitment of Adipose Progenitor Cells -- Orchestration of Adipose Hyperplasia, Hypertrophy, and Remodeling in Male and Female Adipose Tissues -- Expanding the Expandability Hypothesis -- Sex Differences in the Cellularity of Specific Human Adipose Depots: Relationships to Metabolic Dysfunction -- Mechanisms of Adipose Tissue Remodeling and Potential Importance for Depot and Sex Differences in Depot Growth and Metabolism -- Rodents as Models for Sex Differences in Human Adipose Biology -- Summary and Conclusion -- References -- Men Are from Mars, Women Are from Venus: Sex Differences in Insulin Action and Secretion -- Introduction