Suchergebnisse

Spanish Association Against Cancer [PROYE18061FERN]; Health Institute Carlos II [ISCIII/FEDER PI18/01527]; ISCIII-Subdireccion General de Evaluacion y Fomento de la Investigacion (Miguel Servet contract) [CP11/00131]; Plan de Ciencia, Tecnologia e Innovacion from the Asturias Government cofunding (2018-2022/FEDER); Obra Social Cajastur-Liberbank, Spain

This work was supported by European Grants CANCERDIP HEALTH-F2-2007-200620, LSHG-CT-2006-018739-ESTOOLS, LSHC-CT-2006-037297- MCSCs, the Dr. Josef Steiner Cancer Research Foundation Award, the Fondo de Investigaciones Sanitarias Grant PI08-1345, Consolider Grant MEC09-05, the Spanish Association Against Cancer (AECC), Spanish Ministry of Education and Science (SAF2009-07319), the Lilly Foundation Biomedical ResearchAward, Fundacio Cellex, and the Health Department of the Catalan Government (Generalitat de Catalunya). R.S. is supported by BMBF and Deutsche Krebshilfe. J.B. is supported in part by the University College London Cancer Institute Experimental Cancer Medicine Centre and the University College London Hospitals and University College London Comprehensive Biomedical Research Centre. M.E. is an Institucio Catalana de Recerca i Estudis Avanc x ats (ICREA) Research Professor ; Fernandez, A.F., Assenov, Y., Martin-Subero, J.I., Balint, B., Siebert, R., Taniguchi, H., Yamamoto, H., Hidalgo, M., Tan, A.-C., Galm, O., Ferrer, I., Sanchez-Cespedes, M., Villanueva, A., Carmona, J., Sanchez-Mut, J.V., Berdasco, M., Moreno, V., Capella, G., Monk, D., Ballestar, E., Ropero, S., Martinez, R., Sanchez-Carbayo, M., Prosper, F., Agirre, X., Fraga, M.F., Graña, O., Perez-Jurado, L., Mora, J., Puig, S., Prat, J., Badimon, L., Puca, A.A., Meltzer, S.J., Lengauer, T., Bridgewater, J., Bock, C., Esteller, M.

The research leading to these results received funding from the Obra Social "la Caixa" (to ME), the Cellex Foundation (to ME), the European Union's Horizon 2020 research and innovation programme under grant agreement No 727264 Epipharm (to ME), the 2015 Endowment fund for Research into Respiratory Health ("Fonds de Dotation Recherche en Santé Respiratoire"; to MD), the "Fondation ARC pour la recherche sur le cancer - Aide individuelle" (to MD), the Spanish Association Against Cancer (to VD), the Pla Estratègic de Recerca i Innovació en Salut (to SM), the Fondo de Investigación Sanitaria-Fondo Europeo de Desarrollo Regional (PI16/01821 to LMM and PI15/02223, to IG-B), RETTICS grant (RD12/0036/0040 to IG-B), Fundación Merck Salud (to IG-B), Departamento de Salud, Gobierno de Navarra (074-2017, to IGB), the European Commission MSCA IMMUNOMARK-799818 (to IBara), the China Scholarship Council and Karolinska Institutet Fonder (to QX), and the Health and Science Departments of the Generalitat de Catalunya (to ME). We thank IGTP–HUGTP Biobank (PT13/0010/0009) University Hospital Ramon y Cajal-IRYCIS Biobank (PT13/0010/0002), members of the Spanish National Biobanks Network of the Instituto de Salud Carlos III, Andalusia Public Health System Biobank, the Biological Resource Center of the Hospices Civils de Lyon (Tissu-tumorothèque Est), and the Tumor Bank Network of Catalonia for their help with the collection of samples. ; Duruisseaux, M., Martínez-Cardús, A., Calleja-Cervantes, M.E., Moran, S., Castro de Moura, M. , Davalos, V., Piñeyro, D., Sanchez-Cespedes, M., Girard, N., Brevet, M.,Giroux-Leprieur, E., Dumenil, C. Pradotto, M., Bironzo, P., Capelletto, E., Novello, S., Cortot, A. , Copin, M.-C., Karachaliou, N.,Gonzalez-Cao, M. ,Peralta, S., Montuenga, L.M.,Gil-Bazo, I. ,Baraibar, I.,Lozano, M.D., Varela, M. ,Ruffinelli, J.C.,Palmero, R., Nadal, E.,Moran, T., Perez, L., Ramos, I., Xiao, Q.,Fernandez, A.F., Fraga, M.F.,Gut, M., Gut, I. ,Teixidó, C. , Vilariño, N., Prat, A., Reguart, N., Benito, A.,Garrido, P., ...

Plan Nacional de I+D+I FEDER [PI15/00892, PI18/01527]; Government of the Principality of Asturias PCTI-Plan de Ciencia, Tecnologia e Innovacion de Asturias 2018-2022/FEDER [IDI/2018/146]; AECC [PROYE18061FERN]; FGCSIC [0348_CIE_6_E]; IUOPA-ISPA-FINBA (Obra Social Cajastur-Liberbank, Spain); Miguel Servet II fellowship [CPII16/00007]

This work was supported by a European Research Council (ERC) Advanced Grant under the European Community's Seventh Framework Program (FP7/2007-2013)/ERC Grant Agreement No. 268626—EPINORC project (to M. Esteller), the Ministerio de Economía y Competitividad (MINECO) under Grant No. SAF2014-55000-R (to M. Esteller) and the Instituto de Salud Carlos III (ISCIII), under the FIS PI16/01278 Project (to J. Seoane), the Integrated Project of Excellence no. PIE13/00022 (ONCOPROFILE) (to M. Esteller), CIBER 2016 CB16/12/00312 (CIBERONC) (to M. Esteller), co-fnanced by the European Development Regional Fund, 'A way to achieve Europe' ERDF, the AGAUR—Catalan Government (Project No. 2009SGR1315 and 2014SGR633) (to M. Esteller), the Cellex Foundation (to M. Esteller), Obra Social "La Caixa" (to M. Esteller), the CERCA Program and the Health and Science Departments of the Catalan Government (Generalitat de Catalunya) (to M. Esteller) and a grant from the National Health and Medical Research Council of Australia (APP1061551, to TP). M.W. Boudreau is a member of the NIH Chemistry-Biology Interface Training Program (T32-GM070421). ; Janin, M., Ortiz-Barahona, V., de Moura, M.C., Martínez-Cardús, A., Llinàs-Arias, P., Soler, M., Nachmani, D., Pelletier, J., Schumann, U., Calleja-Cervantes, M.E., Moran, S., Guil, S., Bueno-Costa, A., Piñeyro, D., Perez-Salvia, M., Rosselló-Tortella, M., Piqué, L., Bech-Serra, J.J., De La Torre, C., Vidal, A., Martínez-Iniesta, M., Martín-Tejera, J.F., Villanueva, A., Arias, A., Cuartas, I., Aransay, A.M., La Madrid, A.M., Carcaboso, A.M., Santa-Maria, V., Mora, J., Fernandez, A.F., Fraga, M.F., Aldecoa, I., Pedrosa, L., Graus, F., Vidal, N., Martínez-Soler, F., Tortosa, A., Carrato, C., Balañá, C., Boudreau, M.W., Hergenrother, P.J., Kötter, P., Entian, K.-D., Hench, J., Frank, S., Mansouri, S., Zadeh, G., Dans, P.D., Orozco, M., Thomas, G., Blanco, S., Seoane, J., Preiss, T., Pandolfi, P.P., Esteller, M.

This work was supported by the Plan Nacional de I+D+I [2013‐2016/FEDER PI15/00892 to M.F.F. and A.F.F., 2008‐2011/FEDER CP11/00131 to A.F.F.]; the ISCIII‐Subdirección General de Evaluación y Fomento de la Investigación [Miguel Servet contract CP11/00131 to A.F.F.]; Instituto Universitario de Oncología del Principado de Asturias (IUOPA) to [G.F.B.]; Fundación Ramón Areces to [M.F.F.]; and the Asturias Regional Government [GRUPIN14‐052 to M.F.F.]. R.F.P. is supported by the Retención de Jóvenes Talentos Fellowship from the Obra Social Cajastur‐Liberbank. J.R.T. is supported by the Ministry of Economy and Competitiveness Through a Juan de la Cierva Postdoctoral Fellowship [FJCI‐2015‐26965]. The IUOPA is supported by the Obra Social Cajastur‐Liberbank, Spain.

The Asturias Government (PCTI) co-funding 2018-2022/FEDER (IDI/2018/146 to M.F.F.), the Fundación General CSIC (0348_CIE_6_E to M.F.F.), the Health Institute Carlos III (Plan Nacional de I+D+I) co-funding FEDER (PI18/01527 to M.F.F and A.F.F.), the MINECO (DEP2015-69980-P to B.F.G.). R.G.U. is supported by the Centro de Investigación Biomédica en Red de Enfermedades Raras (CIBERER). J.R.T. is supported by a Juan de la Cierva fellowship from the Spanish Ministry of Science and Innovation MCIN/AEI/10.13039/ 501100011033 (IJC2018-036825-I) (.) ; Urdinguio, RG; Tejedor, JR; Fernandez-Sanjurjo, M; Perez, RF; Penarroya, A; Ferrero, C; Codina-Martinez, H; Diez-Planelles, C; Pinto-Hernandez, P; Castilla-Silgado, J; Coto-Vilcapoma, A; Diez-Robles, S; Blanco-Agudin, N; Tomas-Zapico, C; Iglesias-Gutierrez, E; Fernandez-Garcia, B; Fernandez, AF; Fraga, MF

This work was financially supported by: The Plan Nacional de I+D+I co-funding FEDER (PI18/01527); the Government of the Principality of Asturias PCTI-Plan de Ciencia, Tecnología e Innovación de Asturias co-funding 2018-2022/FEDER (IDI/2018/146); AECC (PROYE18061FERN); FGCSIC (0348_CIE_6_E); the Spanish Society of Diabetes (Programme/Funding for Young Researchers to JLFM), and IUOPA-ISPA-FINBA (the IUOPA is supported by the Obra Social Cajastur-Liberbank, Spain); A.F.F is supported by a Miguel Servet II fellowship (contract CPII16/00007); R.F.P. is supported by the Severo Ochoa programme (BP17-114, Government of the Principality of Asturias).

This work has been financially supported by the Plan Nacional de I + D + I 2008–2011/2013–2016/FEDER (PI11/01728 to A.F.F.; PI12/01080 and PI15/00892 to M.F.F.; PI 12/0615 to J.A.R.; PI05/2217 and PI08/0029 to J.G-C); the ISCIII-Subdirección General de Evaluación y Fomento de la Investigación (Miguel Servet contract: CP11/00131 to A.F.F.); IUOPA (to G.F.B. and M.S); Fundacion Cientifica de la AECC (to R.G.U.); Fundación Ramón Areces (to M.F.F); and FICYT (to E.G.T., M.G.G and A.C.);the Madrid Regional Government (S-BIO-02042006 and S2010/BMD-2420 to J.G-C) and the Asturias Regional Government (GRUPIN14-052 to M.F.F.). The IUOPA is supported by the Obra Social Cajastur, Spain. ; Toraño, E.G., Bayón, G.F., del Real, Á., Sierra, M.I., García, M.G., Carella, A., Belmonte, T., Urdinguio, R.G., Cubillo, I., García-Castro, J., Delgado-Calle, J., Pérez-Campo, F.M., Riancho, J.A., Fraga, M.F., Fernández, A.F.

This work has been financially supported by: the Plan Nacional de I+D+I 2013-2016/FEDER (PI15/00892 to M.F.F. and A.F.F.); the ISCIII-Subdirección General de Evaluación y Fomento de la Investigación, and the Plan Nacional de I+D+I 2008-2011/FEDER (CP11/00131 to A.F.F.); IUOPA (to G.F.B., M.I.S. and C.M.); the Fundación Científica de la AECC (to R.G.U.); FICYT (to M.G.G. and A.C.); and the Asturias Regional Government (GRUPIN14-052 to M.F.F.). A.F.F. is also supported from Ministerio de Economía y Competitividad and the European Regional Development Fund (FEDER), Programa Retos de la Sociedad 2015 (RTC-2015-3393-1). The IUOPA is supported by the Obra Social CajasturLiberbank, Spain. ; García, M.G., Carella, A., Urdinguio, R.G., Bayón, G.F., Lopez, V., Tejedor, J.R., Sierra, M.I., García-Toraño, E., Santamarina, P., Perez, R.F., Mangas, C., Astudillo, A., Corte-Torres, M.D., Sáenz-de-Santa-María, I., Chiara, M.-D., Fernández, A.F., Fraga, M.F.

This work is supported by Plan Nacional de I+D+I 2008–2011 and European Union Fondos Feder; Instituto de Salud Carlos III (grant number PI12/02587 and PI16/01318); Red Española de Investigación Renal (REDinREN) (grant number RD12/0021/0018 and 0021, and RD16/0009/0020), Plan de Ciencia, Tecnología e Innovación 2013-2017 del Principado de Asturias (reference GRUPIN-14-030), by the Government of the Basque Country (Etortek Research Programs 2008/2015) the Innovation Technology Department of Bizkaia.

Plan Nacional de I+D+I co-funding FEDER [PI15/00892 and PI18/01527 to M.F.F. and A.F.F.; PI16/01318 and PI14/01244 to C.L.]; ISCIII-Subdireccion General de Evaluación y Fomento de la Investigación, and Plan ´ Nacional de I+D+I 2008–2011/FEDER [CP11/00131 to A.F.F.]; IUOPA (to G.F.B. and M.I.S.); Fundación Científica de la AECC (to R.G.U.); Ministry of Economy and Competitiveness Juan de la Cierva postdoctoral fellowships [FJCI-2015-26965 to J.R.T., IJCI-2015- 23316 to V.L.]; Fundación Ramón Areces (to M.F.F); ´ FICYT (to E.G.T., M.G.G., A.C.); Asturias Regional Government [GRUPIN14-052 to M.F.F.]; Gobierno del Principado de Asturias, PCTI-Plan de Ciencia, Tecnología e Innovación co-funding Fondos FEDER (grant number IDI/2018/146 to M.F.F. and IDI/2018/144 to C.L.); Spanish Ministry of Economy and Competitiveness [SAF-SAF2013-43065 to P.M.]; Asociación Española Contra el Cáncer [AECC-CI-2015]; FERO Foundation, and the ISCIII [PI14-01191 to C.B.]; P.M. acknowledges financial support from The Obra Social La Caixa Fundación Josep Carreras and The Generalitat de Catalunya (SGR330). P.M. an investigator from the Spanish Cell Therapy cooperative network (TERCEL). The IUOPA is supported by the Obra Social Liberbank-Cajastur, Spain. Funding for open access charge: Plan Nacional de I+D+I co-funding FEDER [PI18/01527]. ; Urdinguio, R.G., Lopez, V., Bayón, G.F., Diaz De La Guardia, R., Sierra, M.I., García-Toraño, E., Perez, R.F., García, M.G., Carella, A., Pruneda, P.C., Prieto, C., Dmitrijeva, M., Santamarina, P., Belmonte, T., Mangas, C., Diaconu, E., Ferrero, C., Tejedor, J.R., Fernandez-Morera, J.L., Bravo, C., Bueno, C., Sanjuan-Pla, A., Rodriguez, R.M., Suarez-Alvarez, B., López-Larrea, C., Bernal, T., Colado, E., Balbín, M., García-Suarez, O., Chiara, M.D., Sáenz-De-Santa-María, I., Rodríguez, F., Pando-Sandoval, A., Rodrigo, L., Santos, L., Salas, A., Vallejo-Díaz, J., C Carrera, A., Rico, D., Hernández-López, I., Vayá, A., Ricart, J.M., Seto, E., Sima-Teruel, N., Vaquero, A., Valledor, L., Cañal, M.J., Pisano, D., ...

This work was supported by the Spanish Association Against Cancer (PROYE18061 FERN to M.F.F.), the Asturias Government (PCTI) cofunding 2018- 2022/FEDER (IDI/2018/146 to M.F.F.), Fundación General CSIC (0348_CIE_6_E to M.F.F.), and the Health Institute Carlos III (Plan Nacional de I þ DþI) cofunding FEDER (PI15/00892 and PI18/01527 to M.F.F and A.F.F.). They also acknowledge support from the Ramón Areces Foundation (CIVP18A3891 to P.J.F.M.), the AECC (SIRTBIO to P.J.F.M.), the MICINN (SAF2017-85766-R to P.J.F.M.), a Ramón y Cajal fellowship (MICINN, RYC-2017-22335 to P.J.F.M.), and the European Commission ATTRACT project (777222 to A.P.C.). J.R.T. is supported by a Juan de la Cierva fellowship from the Spanish Ministry of Science and Innovation (FJCI-2015-26965). R.F.P. and P.S.O. are supported by the Severo Ochoa program (BP17-114 and BP17-165, respectively). R.G.U. is supported by the Centro de Investigación Biomédica en Red de Enfermedades Raras (Health Institute Carlos III). L.V. was supported by the UAB Predoctoral training programme (PIF predoctoral fellowships). They also acknowledge support from the IMDEA Food Institute and IUOPA-ISPA-FINBA (the IUOPA is supported by the Obra Social Cajastur-Liberbank, Spain).

This work has been financially supported by: the Plan Nacional de IþDþI 2013–2016/FEDER (PI15/00892 to M.F.F. and A.F.F.; RTC2015-3393-1 to A.F.F.); the ISCIII-Subdirección General de Evaluación y Fomento de la Investigación, and the Plan Nacional de IþDþI 2008–2011/FEDER (CP11/00131 to A.F.F.); IUOPA (to G.F.B. and M.S); the Fundación Científica de la AECC (to R.G.U.); the Fundación Ramón Areces (to M.F.F); FICYT (to E.G.T., M.G.G. and A.C.); and the Asturias Regional Government (GRUPIN14-052 to M.F.F.). Work in P.M. laboratory is supported by the European Research Council (CoG-2014-646903), the Spanish Ministry of Economy-Competitiveness (SAF-SAF2013-43065), the Obra Social La Caixa-Fundació Josep Carreras, and the Generalitat de Catalunya. P.M. is an investigator in the Spanish Cell Therapy cooperative network (TERCEL). The IUOPA is supported by the Obra Social Cajastur-Liberbank, Spain. ; Fernandez, A.F., Bayón, G.F., Sierra, M.I., Urdinguio, R.G., Toraño, E.G., García, M.G., Carella, A., López, V., Santamarina, P., Pérez, R.F., Belmonte, T., Tejedor, J.R., Cobo, I., Menendez, P., Mangas, C., Ferrero, C., Rodrigo, L., Astudillo, A., Ortea, I., Díaz, S.C., Rodríguez-Gonzalez, P., Alonso, J.I.G., Mollejo, M., Meléndez, B., Domínguez, G., Bonilla, F., Fraga, M.F.

This work was supported by grants from project CGL2008-01131 (Departamento de Sanidad del Gobierno Vasco), S-PE08UN45 and PE09BF02 (Departamento de Ciencia y Tecnologia del Gobierno Vasco), BIO2008-04212, and RD06/0020/1019 (Red Tematica de Investigacion Cooperativa en Cancer, RTICC) from the MICINN. The CIBER de Enfermedades Raras is an initiative of the ISCIII. NGB had a doctoral fellowship from the Basque Government (Departamento de Educacion, Universidades e Investigacion).