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"Antiquarian, lawyer, and cat lover Nicolas Fabri de Peiresc (1580-1637), was a 'prince' of the Republic of Letters and the most gifted French intellectual in the generation between Montaigne and Descartes. From Peiresc's study in Aix-en-Provence, his insatiable curiosity poured forth in thousands of letters that traveled the Mediterranean, seeking knowledge of matters mundane and exotic--travel times and insurance premiums, rare manuscripts and objects from the Orient. Mining the remarkable 70,000-page archive of this Provençal humanist and polymath, Peter N. Miller recovers a lost Mediterranean world of the early seventeenth century that was dominated by the sea: the ceaseless activity of merchants, customs officials, and ships' captains at the center of Europe's sprawling maritime networks. Peiresc's Mediterranean World reconstructs the web of connections that linked the bustling port city of Marseille to destinations throughout the Western Mediterranean, North Africa, the Levant, and beyond. As Miller also makes clear, Peiresc's mastery of practical details and his collaboration with local traders and fixers as well as scholars, sheds new light on the structure of knowledge-making in the age of Bacon, Galileo, and Rubens. Miller shows that Peiresc's pursuit of Oriental studies, for example, depended crucially on his abilities as a man of action. Exploring the historian's craft today against the backdrop of Peiresc's diverse research activities, Peiresc's Mediterranean World suggests new possibilities for scholarship on the past, but also for the relationship between the writing of history and its readers"--Provided by publisher

Immanuel Kant''s Religion within the Boundaries of Mere Reason is a seminal text in modern philosophy, ethics, and the philosophy of religion. It is a complex and challenging work, which students and scholars often find difficult to penetrate. This Reader''s Guide provides a ''way in'' to the text including: philosophical and historical context; an overview of key themes; section-by-section analysis of the text; a chapter on its reception and influence as a classic text of the Enlightenment; and a guide for further reading. It highlights the most important themes and ideas, clarifies certain o

1 General considerations on fluorescence spectrometry -- 1.1 Introduction -- 1.2 Molecular photochemistry -- 1.3 Fluorescence instrumentation -- 1.4 Good spectroscopic practice -- 1.5 Fluorescence intensities -- 1.6 Nomenclature in fluorescence spectrometry -- 2 Monochromator wavelength calibration -- 2.1 Introduction -- 2.2 Characteristics of calibration methods -- 2.3 Use of spectral lines from the spectrometer light source -- 2.4 Use of an auxiliary light source -- 2.5 Use of narrow bandwidth fluorescence maxima of inorganic and organic solutes -- 2.6 Conclusions and recommendations -- 3 Stray light in fluorescence spectrometers -- 3.1 Origins of stray light and resultant errors -- 3.2 Stray light in grating monochromators -- 3.3 Summary and recommendations -- 4 Criteria for fluorescence spectrometer sensitivity -- 4.1 Background: inter-instrument comparisons -- 4.2 The limit of detection method -- 4.3 The signal-to-noise ratio method -- 4.4 Summary and recommendations -- 5 Inner filter effects, sample cells and their geometry in fluorescence spectrometry -- 5.1 Inner filter effects -- 5.2 Sample cells -- 5.3 Recommendations -- 6 Temperature effects and photodecomposition in fluorescence spectrometry -- 6.1 Errors caused by temperature effects -- 6.2 Countermeasures and recommendations for temperature effects -- 6.3 Errors caused by photolysis effects -- 6.4 Countermeasures and recommendations -- 7 Correction o excitation and emission spectra -- 7.1 Introduction: the need for correction procedures -- 7.2 Excitation spectra -- 7.3 Emission spectra -- 7.4 Polarization effects -- 7.5 Recommendations -- 8 The determination of quantum yields -- 8.1 Introduction -- 8.2 Primary methods of determining quantum yields -- 8.3 Secondary methods of determining quantum yields: use of fluorescence standards -- 8.4 Other methods of determining quantum yields -- 8.5 Summary and recommendations -- Appendix Corrected excitation and emission spectra.

U.S. overdose deaths attributed to synthetic opioids, such as fentanyl, have increased from under 3,000 in 2013 to nearly 20,000 in 2016, making up half of all opioid‐related overdose deaths. Using web scrapes of darknet markets from 2014 to 2016, I provide historical prices for fentanyl and its most popular analogues and find that fentanyl vendors priced fentanyl in 2014 at a 90% discount compared to an equivalent dose of heroin. Using regression discontinuity, I evaluate the effects of two major law enforcement and regulatory events. I find minimal lasting effects of U.S. legal actions intended to disrupt darknet markets, but there are statistically significant indications of a price increase corresponding with regulatory action in China. Despite these indications of some regulatory success, fentanyl prices remained approximately 90% cheaper than heroin. (JEL I18, K42)