Ethics and Clinical Neuroinnovation: Fundamentals, Stakeholders, Case Studies, and Emerging Issues
Intro -- Foreword -- Preface -- Contents -- Part I: Foundations of Ethics in Clinical Neuroinnovation -- Chapter 1: The Case for Neuroinnovation: Health Burdens Associated with Psychiatric, Addiction-Related, and Co-occurring Disorders -- The Global Burden of Mental Illness and Addiction -- The Individual Burden of Mental Illness and Addiction -- Progress and the Ongoing Burden -- Relief Through Innovation -- Neuroethics and the Foundation for this Book -- References -- Further Reading -- Chapter 2: Neuroinnovation in Medicine: History and Future -- A Historical Perspective -- A Brief History of Neuroimaging -- Functional Magnetic Resonance Imaging (fMRI) -- Distributed Processing and Functional Specialization -- Key Neuroinnovation: Elucidation of the Human Connectome -- From Neuroinnovation to Neurotherapeutics for Depression -- Depression and Prefrontal Cortex Dysfunction -- Depression and the Subgenual Cingulate Cortex (sgCC) -- Deep Brain Stimulation for Depression -- TMS: A Ground-Breaking, Noninvasive Neuromodulatory Treatment for Depression -- The Story of Targeting: Optimizing Coil Placement -- Accelerated Protocols -- Putting It All Together: Stanford Accelerated Intelligent Neuromodulation Therapy (SAINT) -- A Next Big Thing: Focused Ultrasound -- Just Add Nanoparticles -- Closing Thoughts: What Are the Ethical Limits of Neuromodulation? -- References -- Further Reading -- Chapter 3: Clinical Neuroinnovation: Ethical Frameworks and Emerging Issues -- Introduction -- Historical Background to Neuroethics: Principles and Norms -- Assessing Aspects of Clinical Neuroinnovation -- Value (Clinical Need) -- Informed Consent -- Information -- Voluntarism -- Decisional Capacity -- Return of Sensitive Findings -- Novel Ethical Issues in Neuroinnovative Approaches -- Machine Learning -- Brain-Machine Interfaces -- Conclusion -- References.