Sociological Reflexivity and the Sociology of Emotions
In: Sociology and Anthropology, Volume 2, Issue 5, p. 190-195
ISSN: 2331-6187
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In: Sociology and Anthropology, Volume 2, Issue 5, p. 190-195
ISSN: 2331-6187
In: Cultura: international journal of philosophy of culture and axiology, Volume 9, Issue 1, p. 235-247
ISSN: 2065-5002
In: Cuadernos de trabajo social, Volume 30, Issue 2, p. 315-327
ISSN: 1988-8295
Este trabajo averigua y explica cómo personas en riesgo de exclusión social, perceptoras de la Renta de Inclusión Social (RIS) en Navarra no solo reciben un ingreso económico sino también recursos simbólicos (interiorizados y reproducidos) que, frecuentemente, carecen de la dimensión integradora e inclusiva para la que está constituido el recurso.Lo originó la solicitud de la Dirección General de Inclusión y Protección Social del Departamento de Derechos Sociales del Gobierno de Navarra para llevar a cabo un diagnóstico y recabar propuestas incorporables al proceso de modificación de la RIS (de un grupo tradicionalmente excluido de procesos deliberativos).Entre los resultados se identifican discursos tendentes a la responsabilización individual por las situaciones de vulnerabilidad, a exigir a los servicios sociales mayor control sobre el propio endogrupo —asumiendo el deber de auto-control—, o a reclamar el impulso del emprendimiento como vía de acceso al mercado laboral. Se analiza también la dimensión emocional presente en el acceso a estos recursos, con emociones especialmente recurrentes, como la vergüenza o la culpa, vinculadas con la interiorización de juicios responsabilizadores. Resulta también patente una tensa disonancia entre los sentimientos de compasión, empatía y solidaridad hacia las otras personas usuarias, y los de hostilidad y suspicacia que emergen hacia ellas al tomarlas como competidoras rivales por los recursos sociales.
Laccase catalyzes the oxidation and polymerization of phenolic compounds in the presence of oxygen. Herein, we report for the first time that a previous pegylation of laccase enhances the polymerase activity by 3-fold comparing with the native enzyme, as confirmed by UV-Vis spectroscopy. The polymerization of catechol increased only 1.5-fold when polyethyleneglycol (PEG) was added to the medium reaction. Molecular dynamic simulations suggest the formation of a miscible complex of polycatechol and PEG, which is responsible to push the reaction forward. In a negative control experiment set, all catalysts were entrapped inside acrylamide gels and here the native laccase showed a relatively higher activity. These results suggest that the mobility of PEG is a key feature for the enhancement of the reaction. ; This study was supported by Chinese GovernmentScholarship under China Scholarship Council (No. 201606790036), Chinese Foundation Key projects of governmental cooperation in international scientific and technological innovation (No.2 016 YFE0115700), the National Natural Science Foundation of China (No.31470509) and the Fundamental Research Funds for the Central Universities (No.JUSRP51622A). This study was also supported by the Portuguese Foundation for Science and Technology (FCT) under the scope of the strategic funding of UID/BIO/04469/2013 unit and COMPETE2020 (POCI-01–0145-FEDER-006684) and BioTecNorteoperation (NORTE-01–0145-FEDER-000004) fundedb y EuropeanRegional DevelopmentFund under the scope of Norte2020—Programa Operacional Regional do Norte. ...
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Altres ajuts: The sponsors of the study had no role in study design, data collection, data analysis, data interpretation, or writing of the report. The research was funded in part by the European Commission Seventh Framework Programme for research, technological development, and demonstration under grant agreement 305299 (AgedBrainSYSBIO), the Belgian Science Policy Office Interuniversity Attraction Poles program, the Alzheimer Research Foundation (SAO-FRA), the Flemish government-initiated Flanders Impulse Program on Networks for Dementia Research (VIND), the Flemish government-initiated Methusalem Excellence Program, the Research Foundation Flanders (FWO), the VIB Technology Fund, the University of Antwerp Research Fund, Belgium; European Regional Development Fund, the Italian Ministry of Health (Ricerca Corrente and RF-2010-2319722), and the Fondazione Cassa di Risparmio di Pistoia e Pescia grant (2014.0365). ; Premature termination codon (PTC) mutations in the ATP-Binding Cassette, Sub-Family A, Member 7 gene (ABCA7) have recently been identified as intermediate-to-high penetrant risk factor for late-onset Alzheimer's disease (LOAD). High variability, however, is observed in downstream ABCA7 mRNA and protein expression, disease penetrance, and onset age, indicative of unknown modifying factors. Here, we investigated the prevalence and disease penetrance of ABCA7 PTC mutations in a large early onset AD (EOAD)-control cohort, and examined the effect on transcript level with comprehensive third-generation long-read sequencing. We characterized the ABCA7 coding sequence with next-generation sequencing in 928 EOAD patients and 980 matched control individuals. With MetaSKAT rare variant association analysis, we observed a fivefold enrichment (p = 0.0004) of PTC mutations in EOAD patients (3%) versus controls (0.6%). Ten novel PTC mutations were only observed in patients, and PTC mutation carriers in general had an increased familial AD load. In addition, we observed nominal risk reducing trends for three common ...
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